Fumaria densiflora DC. Alkaloids

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Title:Fumaria densiflora DC. Alkaloids
Creators:
Táborská, Eva
Bochořáková, Hana
Soušek, Jaromír
Sedmera, Petr
Vavrečková, Ctirada
Šimánek, Vilím
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 61, 7, pp. 1064-1072
Uncontrolled Keywords:<i>Fumaria densiflora</i> DC., Cytoprotective effect, Isoquinoline alkaloids

Abstract

Twenty isoquinoline alkaloids were identified in the aerial part of <i>Fumaria densiflora</i> DC. In addition to bicuculline, densiflorine, fumaritine, fumariline, scoulerine, coptisine, cryptopine, parfumine, protopine, and sinactine which have been found previously, the following alkaloids were isolated for the first time from this species: adlumine, fumaricine, fumaritridine, fumarophycine, fumarofine, corytuberine, <i>cis</i>-<i>N</i>-methylstylopinium iodide, stylopine, and two new 1-benzylisoquinoline alkaloids, viz. fumaflorine and fumaflorine methyl ester. The cytoprotectivity of extracts of <i>F</i>. <i>densiflora </i>and <i>F. officinalis</i>, and that of protopine, cryptopine, and parfumine was tested on primary cultures of rat hepatocytes intoxicated with carbon tetrachloride. The cytoprotective effect of the extracts is associated with the alkaloids.

Title:Fumaria densiflora DC. Alkaloids
Creators:
Táborská, Eva
Bochořáková, Hana
Soušek, Jaromír
Sedmera, Petr
Vavrečková, Ctirada
Šimánek, Vilím
Uncontrolled Keywords:<i>Fumaria densiflora</i> DC., Cytoprotective effect, Isoquinoline alkaloids
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:61
Number:7
Page Range:pp. 1064-1072
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19961064UNSPECIFIED
ID Code:1010
Item Type:Article
Deposited On:06 Feb 2009 17:05
Last Modified:06 Feb 2009 16:05

Citation

Táborská, Eva; Bochořáková, Hana; Soušek, Jaromír; Sedmera, Petr; Vavrečková, Ctirada; Šimánek, Vilím (1996) Fumaria densiflora DC. Alkaloids. Collection of Czechoslovak Chemical Communications, 61 (7). pp. 1064-1072. ISSN 0010-0765

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