Syntheses and Spectral Properties of Unsymmetrically 3,5-Disubstituted 2,6-Dimethyl-1,4-dihydropyridines

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Title:Syntheses and Spectral Properties of Unsymmetrically 3,5-Disubstituted 2,6-Dimethyl-1,4-dihydropyridines
Creators:
Ilavský, Dušan
Milata, Viktor
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 61, 8, pp. 1233-1243
Uncontrolled Keywords:Hantzsch synthesis, 1,4-Dihydropyridines, alkylation

Abstract

Unsymmetrically 3,5-disubstituted 4-(5-X-2-furyl)-2,6-dimethyl-1,4-dihydropyridines (where X = H, Br, NO<sub>2</sub>) have been synthesized and characterized by spectral methods (IR, UV, <sup>1</sup>H NMR and MS). The modified Hantzsch method made it possible to prepare the title compounds as well as their <i>N</i>-alkylated derivatives. The paper also describes the <i>N</i>-alkylation of sodium salts of substituted 1,4-dihydropyridines using the phase-transfer catalysis.

Title:Syntheses and Spectral Properties of Unsymmetrically 3,5-Disubstituted 2,6-Dimethyl-1,4-dihydropyridines
Creators:
Ilavský, Dušan
Milata, Viktor
Uncontrolled Keywords:Hantzsch synthesis, 1,4-Dihydropyridines, alkylation
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:61
Number:8
Page Range:pp. 1233-1243
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19961233UNSPECIFIED
ID Code:1028
Item Type:Article
Deposited On:06 Feb 2009 17:05
Last Modified:06 Feb 2009 16:06

Citation

Ilavský, Dušan; Milata, Viktor (1996) Syntheses and Spectral Properties of Unsymmetrically 3,5-Disubstituted 2,6-Dimethyl-1,4-dihydropyridines. Collection of Czechoslovak Chemical Communications, 61 (8). pp. 1233-1243. ISSN 0010-0765

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