trans-Hydrindanes by Reduction: Synthesis of Dihydro-B-nortestosterone

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Title:trans-Hydrindanes by Reduction: Synthesis of Dihydro-B-nortestosterone
Creators:
Kasal, Alexander
Chodounská, Hana
Szczepek, Wojciech J.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 61, 9, pp. 1386-1395
Uncontrolled Keywords:Catalytic hydrogenation, Stereochemistry, Diimide reduction

Abstract

Reduction with diimide was employed in the synthesis of potential antiandrogens - 17β-hydroxy-B-nor-5α-androstan-3-one (<strong>26</strong>) and its 17α-methyl derivative (<strong>25</strong>). Other methods of reduction (hydroboration, catalytic hydrogenation) were less effective.

Title:trans-Hydrindanes by Reduction: Synthesis of Dihydro-B-nortestosterone
Creators:
Kasal, Alexander
Chodounská, Hana
Szczepek, Wojciech J.
Uncontrolled Keywords:Catalytic hydrogenation, Stereochemistry, Diimide reduction
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:61
Number:9
Page Range:pp. 1386-1395
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19961386UNSPECIFIED
ID Code:1044
Item Type:Article
Deposited On:06 Feb 2009 17:06
Last Modified:06 Feb 2009 16:06

Citation

Kasal, Alexander; Chodounská, Hana; Szczepek, Wojciech J. (1996) trans-Hydrindanes by Reduction: Synthesis of Dihydro-B-nortestosterone. Collection of Czechoslovak Chemical Communications, 61 (9). pp. 1386-1395. ISSN 0010-0765

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