New Synthesis of Important Prostanoid Intermediate

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Title:New Synthesis of Important Prostanoid Intermediate
Creators:
Svoboda, Jiří
Kozmík, Václav
Veselý, Ivan
Paleček, Jaroslav
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 61, 10, pp. 1509-1519
Uncontrolled Keywords:Misoprostol, Prostaglandins, Acetals

Abstract

New synthesis of intermediates for the preparation of prostaglandin analogs of the E<sub>1</sub> series is described. The simple synthesis starts from commercially accessible Corey acetate <strong>1</strong> and makes use of simultaneous protection of the two hydroxy groups in the form of cyclic acetal. No expensive protecting reagents are required and the synthetic sequence leading to the end product is shorter.

Title:New Synthesis of Important Prostanoid Intermediate
Creators:
Svoboda, Jiří
Kozmík, Václav
Veselý, Ivan
Paleček, Jaroslav
Uncontrolled Keywords:Misoprostol, Prostaglandins, Acetals
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:61
Number:10
Page Range:pp. 1509-1519
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19961509UNSPECIFIED
ID Code:1054
Item Type:Article
Deposited On:06 Feb 2009 17:06
Last Modified:06 Feb 2009 16:06

Citation

Svoboda, Jiří; Kozmík, Václav; Veselý, Ivan; Paleček, Jaroslav (1996) New Synthesis of Important Prostanoid Intermediate. Collection of Czechoslovak Chemical Communications, 61 (10). pp. 1509-1519. ISSN 0010-0765

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