Solid-Phase Organic Synthesis: Creation of Carbon-Carbon Double Bonds Under Mild Conditions by Wittig-Type Reactions

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Title:Solid-Phase Organic Synthesis: Creation of Carbon-Carbon Double Bonds Under Mild Conditions by Wittig-Type Reactions
Creators:
Vágner, Josef
Krchňák, Viktor
Lebl, Michal
Barany, George
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 61, 12, pp. 1697-1702
Uncontrolled Keywords:Wittig reaction, Combinatorial chemistry, Solid-phase synthesis

Abstract

Phosphorane ylides and phosphonate anions react smoothly with resin-bound aldehydes and ketones to provide alkenes in good yields and purities (assessed after cleavage of acid-labile PAL anchor to support). The reactions of aldehydes give excellent stereoselectivities. Effective conditions have been developed for carrying out these transformations. <p>

Title:Solid-Phase Organic Synthesis: Creation of Carbon-Carbon Double Bonds Under Mild Conditions by Wittig-Type Reactions
Creators:
Vágner, Josef
Krchňák, Viktor
Lebl, Michal
Barany, George
Uncontrolled Keywords:Wittig reaction, Combinatorial chemistry, Solid-phase synthesis
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:61
Number:12
Page Range:pp. 1697-1702
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19961697UNSPECIFIED
ID Code:1075
Item Type:Article
Deposited On:06 Feb 2009 17:06
Last Modified:06 Feb 2009 16:06

Citation

Vágner, Josef; Krchňák, Viktor; Lebl, Michal; Barany, George (1996) Solid-Phase Organic Synthesis: Creation of Carbon-Carbon Double Bonds Under Mild Conditions by Wittig-Type Reactions. Collection of Czechoslovak Chemical Communications, 61 (12). pp. 1697-1702. ISSN 0010-0765

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