Syntheses of Steroid O-(3-Carboxypropyl)oximes

[img]PDF - Authorized users only
Language: English
92Kb
Title:Syntheses of Steroid O-(3-Carboxypropyl)oximes
Creators:
Slavíková, Tereza
Pouzar, Vladimír
Černý, Ivan
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 62, 3, pp. 457-470
Uncontrolled Keywords:<i>E/Z</i> Isomers, <i>O</i>-Alkylated oximes

Abstract

The syntheses of <i>O</i>-(3-carboxypropyl)oxime derivatives, <i>i.e.</i> bis-homologues of <i>O</i>-(carboxymethyl)oxime derivatives (CMO), derived from dehydroepiandrosterone, testosterone and estradiol are presented. Both the reaction of steroid ketone with <i>O</i>-(3-carboxypropyl)hydroxylamine, and the reaction of sodium salt of steroid oxime with ethyl 4-bromobutyrate were alternatively evaluated, together with some other methods using successive chain lengthening. The compatibility with acetyl and methoxymethyl protecting groups was studied.

Title:Syntheses of Steroid O-(3-Carboxypropyl)oximes
Creators:
Slavíková, Tereza
Pouzar, Vladimír
Černý, Ivan
Uncontrolled Keywords:<i>E/Z</i> Isomers, <i>O</i>-Alkylated oximes
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:62
Number:3
Page Range:pp. 457-470
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19970457UNSPECIFIED
ID Code:1130
Item Type:Article
Deposited On:06 Feb 2009 17:06
Last Modified:06 Feb 2009 16:06

Citation

Slavíková, Tereza; Pouzar, Vladimír; Černý, Ivan (1997) Syntheses of Steroid O-(3-Carboxypropyl)oximes. Collection of Czechoslovak Chemical Communications, 62 (3). pp. 457-470. ISSN 0010-0765

Repository Staff Only: item control page