Cyclic Dipeptides with 1-Aminocyclopropane-1-carboxylic Acid

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Title:Cyclic Dipeptides with 1-Aminocyclopropane-1-carboxylic Acid
Creators:
Kasafírek, Evžen
Moural, Jaroslav
Vinšová, Jarmila
Šturc, Antonín
Taimr, Jan
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 62, 6, pp. 941-947
Uncontrolled Keywords:1-Aminocyclopropane-1-carboxylic acid, Dipeptides, 2,5-Piperazinedione derivatives

Abstract

Cyclic dipeptides of the formula cyclo(-Acc-X-), where Acc = 1-aminocyclopropane-1-carboxylic acid, X = Gly, Ala, Val, Leu, Phe or Tyr, were synthesized. The prepared 2,5-piperazinediones showed no proliferative or antiproliferative activity on normal human embryo cells as well as on HL60 leukemia cells. Results of trace memory assays in mice were negative.

Title:Cyclic Dipeptides with 1-Aminocyclopropane-1-carboxylic Acid
Creators:
Kasafírek, Evžen
Moural, Jaroslav
Vinšová, Jarmila
Šturc, Antonín
Taimr, Jan
Uncontrolled Keywords:1-Aminocyclopropane-1-carboxylic acid, Dipeptides, 2,5-Piperazinedione derivatives
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:62
Number:6
Page Range:pp. 941-947
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19970941UNSPECIFIED
ID Code:1175
Item Type:Article
Deposited On:06 Feb 2009 17:07
Last Modified:06 Feb 2009 16:07

Citation

Kasafírek, Evžen; Moural, Jaroslav; Vinšová, Jarmila; Šturc, Antonín; Taimr, Jan (1997) Cyclic Dipeptides with 1-Aminocyclopropane-1-carboxylic Acid. Collection of Czechoslovak Chemical Communications, 62 (6). pp. 941-947. ISSN 0010-0765

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