Synthesis and Reactions of 8-Hydrazinofuro[2',3':4,5]pyrrolo-[1,2-d][1,2,4]triazines

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Title:Synthesis and Reactions of 8-Hydrazinofuro[2',3':4,5]pyrrolo-[1,2-d][1,2,4]triazines
Creators:
Krutošíková, Alžbeta
Mastik, Slavomír
Dandárová, Miloslava
Lyčka, Antonín
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 62, 10, pp. 1612-1622
Uncontrolled Keywords:Hydrazones, Furo[2',3':4,5]pyrrolo[1,2-<i>d</i>][1,2,4]triazolo[3,4-<i>f</i>][1,2,4]triazine, Furo[2',3':4,5]pyrrolo[1,2-<i>d</i>][1,2,4]triazine, Cyclization, Semicarbazones

Abstract

5-Ethyl-8-hydrazinofuro[2',3':4,5]pyrrolo[1,2-<i>d</i>][1,2,4]triazine (<strong>4a</strong>) and its 2-methyl derivative <strong>4b</strong> were prepared from 4<i>H</i>-furo[3,2-<i>b</i>]pyrrole-5-carbohydrazides <strong>1a </strong>and <strong>1b,</strong> respectively. Compounds <strong>1a</strong> and <strong>1b</strong> reacted with triethyl orthopropionate to give <strong>2a</strong> and <strong>2b</strong> which afforded with phosphorus(V) sulfide corresponding thiones <strong>3a</strong> and <strong>3b</strong>. The title compounds <strong>4a</strong> and <strong>4b</strong> were made by treatment of <strong>3a</strong> and <strong>3b</strong> with hydrazine hydrate. By reactions of triethyl orthoesters with the title compounds and similar derivatives furo[2'3':4,5]pyrrolo[1,2-<i>d</i>][1,2,4]triazolo[3,4-<i>f</i>][1,2,4]triazines <strong>5a-5j </strong>were prepared. Reactions of compounds <strong>4</strong> with some aldehydes and isocyanates led to hydrazones <strong>6a-6c</strong> and semicarbazones <strong>7a</strong> and <strong>7b</strong>, respectively.

Title:Synthesis and Reactions of 8-Hydrazinofuro[2',3':4,5]pyrrolo-[1,2-d][1,2,4]triazines
Creators:
Krutošíková, Alžbeta
Mastik, Slavomír
Dandárová, Miloslava
Lyčka, Antonín
Uncontrolled Keywords:Hydrazones, Furo[2',3':4,5]pyrrolo[1,2-<i>d</i>][1,2,4]triazolo[3,4-<i>f</i>][1,2,4]triazine, Furo[2',3':4,5]pyrrolo[1,2-<i>d</i>][1,2,4]triazine, Cyclization, Semicarbazones
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:62
Number:10
Page Range:pp. 1612-1622
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19971612UNSPECIFIED
ID Code:1236
Item Type:Article
Deposited On:06 Feb 2009 17:07
Last Modified:06 Feb 2009 16:07

Citation

Krutošíková, Alžbeta; Mastik, Slavomír; Dandárová, Miloslava; Lyčka, Antonín (1997) Synthesis and Reactions of 8-Hydrazinofuro[2',3':4,5]pyrrolo-[1,2-d][1,2,4]triazines. Collection of Czechoslovak Chemical Communications, 62 (10). pp. 1612-1622. ISSN 0010-0765

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