Substituent Effect on Acidity of Substituted 2-(4-Nitrobenzoylamino)alkanamides in Methanol-Dimethyl Sulfoxide Mixtures

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Title:Substituent Effect on Acidity of Substituted 2-(4-Nitrobenzoylamino)alkanamides in Methanol-Dimethyl Sulfoxide Mixtures
Creators:
Mitaš, Petr
Sedlák, Miloš
Kaválek, Jaromír
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 63, 1, pp. 85-93
Uncontrolled Keywords:Solvent effects, 2-(4-Nitrobenzoylamino)alkanamides, Dissociation constants, Steric effects, Substituent effects

Abstract

The dissociation constants of substituted 2-(4-nitrobenzoylamino)alkanamides, <i>N</i>-[2-(4-nitrobenzoylamino)alkanoyl]pyrrolidines, and <i>N</i>-alkyl-4-nitrobenzamides have been measured spectrophotometrically in 60 and 80% v/v DMSO. The p<i>K</i><sub>A</sub> values of these <i>N</i>-acids are discussed from the point of view of substituents at the acetamide α-carbon atom.

Title:Substituent Effect on Acidity of Substituted 2-(4-Nitrobenzoylamino)alkanamides in Methanol-Dimethyl Sulfoxide Mixtures
Creators:
Mitaš, Petr
Sedlák, Miloš
Kaválek, Jaromír
Uncontrolled Keywords:Solvent effects, 2-(4-Nitrobenzoylamino)alkanamides, Dissociation constants, Steric effects, Substituent effects
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:63
Number:1
Page Range:pp. 85-93
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19980085UNSPECIFIED
ID Code:1276
Item Type:Article
Deposited On:06 Feb 2009 17:08
Last Modified:06 Feb 2009 16:08

Citation

Mitaš, Petr; Sedlák, Miloš; Kaválek, Jaromír (1998) Substituent Effect on Acidity of Substituted 2-(4-Nitrobenzoylamino)alkanamides in Methanol-Dimethyl Sulfoxide Mixtures. Collection of Czechoslovak Chemical Communications, 63 (1). pp. 85-93. ISSN 0010-0765

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