Electrochemical Investigations of the Nickel(II)-Penicillamine System. Inert and Labile Complexes Detected by Polarography

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Title:Electrochemical Investigations of the Nickel(II)-Penicillamine System. Inert and Labile Complexes Detected by Polarography
Creators:
Ion, Ana
Banica, Florinel G.
Luca, Constantin
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 63, 2, pp. 187-198
Uncontrolled Keywords:Amino acids, Chelates, Electrochemistry, Nickel toxicology, Nickel complexes, Penicillamine

Abstract

The effect of penicillamine on nickel diffusion current demonstrates that Ni<sub>2</sub><sup>2-</sup> is a kinetically inert complex whereas NiL is labile (L<sup>2-</sup> = (CH<sub>3</sub>)<sub>2</sub>C(S<sup>-</sup>)CH(NH<sub>2</sub>)COO<sup>-</sup>)). The difference in kinetic stability between the analogous bis-ligand complexes of Ni(II) with either penicillamine or cysteine is tentatively explained taking into account their structures. It is suggested that nickel detoxication by chelate ligands depends on the inert character rather than on the thermodynamic stability of the relevant nickel complex.

Title:Electrochemical Investigations of the Nickel(II)-Penicillamine System. Inert and Labile Complexes Detected by Polarography
Creators:
Ion, Ana
Banica, Florinel G.
Luca, Constantin
Uncontrolled Keywords:Amino acids, Chelates, Electrochemistry, Nickel toxicology, Nickel complexes, Penicillamine
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:63
Number:2
Page Range:pp. 187-198
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19980187UNSPECIFIED
ID Code:1286
Item Type:Article
Deposited On:06 Feb 2009 17:08
Last Modified:06 Feb 2009 16:08

Citation

Ion, Ana; Banica, Florinel G.; Luca, Constantin (1998) Electrochemical Investigations of the Nickel(II)-Penicillamine System. Inert and Labile Complexes Detected by Polarography. Collection of Czechoslovak Chemical Communications, 63 (2). pp. 187-198. ISSN 0010-0765

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