Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases

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Title:Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases
Creators:
Weignerová, Lenka
Suzuki, Yukio
Huňková, Zdenka
Sedmera, Petr
Havlíček, Vladimír
Marek, Radek
Křen, Vladimír
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 64, 8, pp. 1325-1334
Uncontrolled Keywords:Glycosidases, Vitamins, Biocatalysis, Pyridoxine, Glycosides, Enzymatic glycosylation

Abstract

The reactions of glycosidases with pyridoxine were used for testing their ability to make new glycosidic bonds. Of 35 glycosidases examined, some exhibited regiospecificity towards one primary alcoholic group; glycosylation of phenolic hydroxyl group was not observed. A series of new glycosides of pyridoxine, 2-acetamido-2-deoxy-β-D-glucopyranosides, α-D-manno- pyranosides, and one α-D-galactopyranoside were prepared and completely characterized by MS and NMR. <p>

Title:Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases
Creators:
Weignerová, Lenka
Suzuki, Yukio
Huňková, Zdenka
Sedmera, Petr
Havlíček, Vladimír
Marek, Radek
Křen, Vladimír
Uncontrolled Keywords:Glycosidases, Vitamins, Biocatalysis, Pyridoxine, Glycosides, Enzymatic glycosylation
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:64
Number:8
Page Range:pp. 1325-1334
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19991325UNSPECIFIED
ID Code:1559
Item Type:Article
Deposited On:06 Feb 2009 17:10
Last Modified:06 Feb 2009 16:10

Citation

Weignerová, Lenka; Suzuki, Yukio; Huňková, Zdenka; Sedmera, Petr; Havlíček, Vladimír; Marek, Radek; Křen, Vladimír (1999) Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases. Collection of Czechoslovak Chemical Communications, 64 (8). pp. 1325-1334. ISSN 0010-0765

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