Synthesis and Resolution of a New C2-Symmetric Chiral Bis-Aniline, trans-1,2-Bis(2-aminophenyl)cyclopentane

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Title:Synthesis and Resolution of a New C2-Symmetric Chiral Bis-Aniline, trans-1,2-Bis(2-aminophenyl)cyclopentane
Creators:
Yang, Jin-Song
Kondo, Kazuhiro
Murakami, Yasuoki
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 65, 4, pp. 549-554
Uncontrolled Keywords:Amines, Asymmetric catalysis, N-Ligand, <i>C</i><sub>2</sub>-Symmetry, Chiral bis-anilines, Axial chirality

Abstract

New <i>C</i><sub>2</sub>-symmetric <i>trans</i>-1,2-bis(2-aminophenyl)cyclopentanes <strong>2a</strong> and <strong>2b</strong> were synthesized in optically pure forms (99% ee) from the known racemic <i>trans</i>-1,2-bis(2-hydroxyphenyl)cyclopentane (<strong>3</strong>) by the conversion to its bis-triflate <strong>4</strong> followed by the Buchwald amination and resolution. <p>

Title:Synthesis and Resolution of a New C2-Symmetric Chiral Bis-Aniline, trans-1,2-Bis(2-aminophenyl)cyclopentane
Creators:
Yang, Jin-Song
Kondo, Kazuhiro
Murakami, Yasuoki
Uncontrolled Keywords:Amines, Asymmetric catalysis, N-Ligand, <i>C</i><sub>2</sub>-Symmetry, Chiral bis-anilines, Axial chirality
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:65
Number:4
Page Range:pp. 549-554
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20000549UNSPECIFIED
ID Code:1660
Item Type:Article
Deposited On:06 Feb 2009 17:11
Last Modified:06 Feb 2009 16:11

Citation

Yang, Jin-Song; Kondo, Kazuhiro; Murakami, Yasuoki (2000) Synthesis and Resolution of a New C2-Symmetric Chiral Bis-Aniline, trans-1,2-Bis(2-aminophenyl)cyclopentane. Collection of Czechoslovak Chemical Communications, 65 (4). pp. 549-554. ISSN 0010-0765

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