Preparation of Unlabelled and [3H]-Labelled Epitestosterone and Its Metabolites

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Title:Preparation of Unlabelled and [3H]-Labelled Epitestosterone and Its Metabolites
Creators:
Kasal, Alexander
Fuksová, Květa
Pouzar, Vladimír
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 58, 3, pp. 600-611

Abstract

Cold as well as [<sup>3</sup>H]-labelled substrates and metabolites <i>IX - XI, XV, XVI, XX - XXII, XXIV, XXV</i> and <i>XXVIII</i> were prepared by catalytic hydrogenation of epitestosterone (<i>VIII</i>) and ∆<sup>1</sup>-dehydroepitestosterone (<i>XIII</i>). The key step in the preparation of compound <i>XXVIII</i> was reaction of 3β-tosylates <i>XXVI</i> and <i>XXX</i> with potassium nitrite in dimethyl sulfoxide.

Title:Preparation of Unlabelled and [3H]-Labelled Epitestosterone and Its Metabolites
Creators:
Kasal, Alexander
Fuksová, Květa
Pouzar, Vladimír
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:58
Number:3
Page Range:pp. 600-611
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19930600UNSPECIFIED
ID Code:184
Item Type:Article
Deposited On:06 Feb 2009 16:58
Last Modified:06 Feb 2009 15:58

Citation

Kasal, Alexander; Fuksová, Květa; Pouzar, Vladimír (1993) Preparation of Unlabelled and [3H]-Labelled Epitestosterone and Its Metabolites. Collection of Czechoslovak Chemical Communications, 58 (3). pp. 600-611. ISSN 0010-0765

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