Synthesis of (Trifluoromethyl)aziridines in 1,1,1,3,3,3-Hexafluoropropan-2-ol: First Example of Coupling Reactions of Fluoral, an Amine and a Diazo Compound

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Title:Synthesis of (Trifluoromethyl)aziridines in 1,1,1,3,3,3-Hexafluoropropan-2-ol: First Example of Coupling Reactions of Fluoral, an Amine and a Diazo Compound
Creators:
Spanedda, Maria Vittoria
Crousse, Benoit
Narizuka, Satoru
Bonnet-Delpon, Danièle
Bégué, Jean-Pierre
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 67, 9, pp. 1359-1365
Uncontrolled Keywords:Fluorine, Hexafluoropropan-2-ol, Diazo compounds, Imines, Aziridines, Aziridination

Abstract

The influence of solvent on the Yb(OTf)<sub>3</sub> or BF<sub>3</sub>·Et<sub>2</sub>O-catalyzed reaction of (trifluoromethyl)aldimines with ethyl diazoacetate has been investigated. The reaction of fluoral ethyl hemiacetal, an aromatic amine, and ethyl diazoacetate could be performed in 1,1,1,3,3,3-hexafluoropropan-2-ol to provide the corresponding (trifluoromethyl)aziridines. <p>

Title:Synthesis of (Trifluoromethyl)aziridines in 1,1,1,3,3,3-Hexafluoropropan-2-ol: First Example of Coupling Reactions of Fluoral, an Amine and a Diazo Compound
Creators:
Spanedda, Maria Vittoria
Crousse, Benoit
Narizuka, Satoru
Bonnet-Delpon, Danièle
Bégué, Jean-Pierre
Uncontrolled Keywords:Fluorine, Hexafluoropropan-2-ol, Diazo compounds, Imines, Aziridines, Aziridination
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:67
Number:9
Page Range:pp. 1359-1365
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20021359UNSPECIFIED
ID Code:1999
Item Type:Article
Deposited On:06 Feb 2009 17:14
Last Modified:06 Feb 2009 16:14

Citation

Spanedda, Maria Vittoria; Crousse, Benoit; Narizuka, Satoru; Bonnet-Delpon, Danièle; Bégué, Jean-Pierre (2002) Synthesis of (Trifluoromethyl)aziridines in 1,1,1,3,3,3-Hexafluoropropan-2-ol: First Example of Coupling Reactions of Fluoral, an Amine and a Diazo Compound. Collection of Czechoslovak Chemical Communications, 67 (9). pp. 1359-1365. ISSN 0010-0765

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