Intramolecular Mannich Reaction of 2-Oxotryptamine and Homologues with Oxo Reagents Yielding Spiro Compounds. Part II

[img]PDF - Authorized users only
Language: English
124Kb
Title:Intramolecular Mannich Reaction of 2-Oxotryptamine and Homologues with Oxo Reagents Yielding Spiro Compounds. Part II
Creators:
Dörnyei, Gábor
Incze, Mária
Kajtár-Peredy, Mária
Szántay, Csaba
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 67, 11, pp. 1669-1680
Uncontrolled Keywords:Intramolecular Mannich reaction, Cyclizations, Oxindoles, Spirocyclic compounds, Piperidines, Ketones, Indoles, Alkaloids, Pyrrolidines

Abstract

2-Oxotryptamine and its homo derivative undergo intramolecular Mannich-type cyclization&nbsp;with acetone and other ketones to give spiro[indole-3,3'-pyrrolidin]-2-ones and spiro[indole-3,3'-piperidin]-2-ones. A similar reaction with the bis-homologue of 2-oxotryptamine to yield spiro[azepane-3,3'-indol]-2'-ones was unsuccessful. <p>

Title:Intramolecular Mannich Reaction of 2-Oxotryptamine and Homologues with Oxo Reagents Yielding Spiro Compounds. Part II
Creators:
Dörnyei, Gábor
Incze, Mária
Kajtár-Peredy, Mária
Szántay, Csaba
Uncontrolled Keywords:Intramolecular Mannich reaction, Cyclizations, Oxindoles, Spirocyclic compounds, Piperidines, Ketones, Indoles, Alkaloids, Pyrrolidines
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:67
Number:11
Page Range:pp. 1669-1680
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20021669UNSPECIFIED
ID Code:2025
Item Type:Article
Deposited On:06 Feb 2009 17:14
Last Modified:06 Feb 2009 16:15

Citation

Dörnyei, Gábor; Incze, Mária; Kajtár-Peredy, Mária; Szántay, Csaba (2002) Intramolecular Mannich Reaction of 2-Oxotryptamine and Homologues with Oxo Reagents Yielding Spiro Compounds. Part II. Collection of Czechoslovak Chemical Communications, 67 (11). pp. 1669-1680. ISSN 0010-0765

Repository Staff Only: item control page