Synthesis of Homochiral Acyclic Mono- and Bis(α-amino acid)s with Oligo(oxyethylene) Chains

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Title:Synthesis of Homochiral Acyclic Mono- and Bis(α-amino acid)s with Oligo(oxyethylene) Chains
Creators:
Bělohradský, Martin
Ridvan, Luděk
Závada, Jiří
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 68, 7, pp. 1319-1325
Uncontrolled Keywords:Nucleophilic ring-opening reaction, Podands, Oligo(ethylene glycol)s, Aziridines, Amino acids, Crown ethers

Abstract

Synthesis of homochiral α-amino acids <strong>3a</strong>-<strong>3e</strong> and bis(α-amino acid)s <strong>4a</strong>-<strong>4e</strong> <i>via</i> BF<sub>3</sub>·Et<sub>2</sub>O-catalyzed ring-opening of methyl (<i>S</i>)-1-[(benzyloxy)carbonyl]aziridine-2-carboxylate (<strong>7</strong>) with oligo(ethylene glycol)s and subsequent acid hydrolysis is reported. <p>

Title:Synthesis of Homochiral Acyclic Mono- and Bis(α-amino acid)s with Oligo(oxyethylene) Chains
Creators:
Bělohradský, Martin
Ridvan, Luděk
Závada, Jiří
Uncontrolled Keywords:Nucleophilic ring-opening reaction, Podands, Oligo(ethylene glycol)s, Aziridines, Amino acids, Crown ethers
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:68
Number:7
Page Range:pp. 1319-1325
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20031319UNSPECIFIED
ID Code:2122
Item Type:Article
Deposited On:06 Feb 2009 17:15
Last Modified:06 Feb 2009 16:15

Citation

Bělohradský, Martin; Ridvan, Luděk; Závada, Jiří (2003) Synthesis of Homochiral Acyclic Mono- and Bis(α-amino acid)s with Oligo(oxyethylene) Chains. Collection of Czechoslovak Chemical Communications, 68 (7). pp. 1319-1325. ISSN 0010-0765

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