Synthesis of New Chiral 1,2-Disubstituted Ferrocenes

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Title:Synthesis of New Chiral 1,2-Disubstituted Ferrocenes
Creators:
Fleischer, Ivana
Toma, Štefan
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 69, 2, pp. 330-338
Uncontrolled Keywords:Planar chirality, Ferrocenecarbaldehydes, Oxidations, Diastereoselective reactions, Ferrocenes, Pyrrolidines

Abstract

Synthesis of six chiral 1,2-disubstituted ferrocene derivatives is described starting from (<i>S</i>)-{[2-(methoxymethyl)pyrrolidin-1-yl]methyl}ferrocene (<strong>2</strong>) and {[<i>N</i>-((1<i>R</i>,2<i>S</i>)-methoxy-1-methyl-2-phenethyl)-<i>N</i>-methylamino]methyl}ferrocene (<strong>3</strong>). Oxidation of the (<i>N</i>-substituted aminomethyl)ferrocenes with active MnO<sub>2</sub> furnished the corresponding 2-substituted ferrocenecarbaldehydes. <p>

Title:Synthesis of New Chiral 1,2-Disubstituted Ferrocenes
Creators:
Fleischer, Ivana
Toma, Štefan
Uncontrolled Keywords:Planar chirality, Ferrocenecarbaldehydes, Oxidations, Diastereoselective reactions, Ferrocenes, Pyrrolidines
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:69
Number:2
Page Range:pp. 330-338
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20040330UNSPECIFIED
ID Code:2213
Item Type:Article
Deposited On:06 Feb 2009 17:16
Last Modified:06 Feb 2009 16:16

Citation

Fleischer, Ivana; Toma, Štefan (2004) Synthesis of New Chiral 1,2-Disubstituted Ferrocenes. Collection of Czechoslovak Chemical Communications, 69 (2). pp. 330-338. ISSN 0010-0765

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