Facile Synthesis of Aryl-Substituted 1,2,5,6-Tetrahydropyrimidines and Their Stereochemical Investigation

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Title:Facile Synthesis of Aryl-Substituted 1,2,5,6-Tetrahydropyrimidines and Their Stereochemical Investigation
Creators:
Chebanov, Valentin A.
Muravyova, Elena A.
Sadchikova, Yulia V.
Desenko, Sergey M.
Chernenko, Vitaly N.
Kobzar, Kiril M.
Musatov, Vladimir I.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 69, 4, pp. 897-904
Uncontrolled Keywords:Heterocyclizations, Multicomponent reactions, Pyrimidines, Chalcones, Synthetic methods, Nitrogen heterocycles, Structure elucidation, 1,2,5,6-Tetrahydropyrimidines, NMR spectroscopy

Abstract

The present work is devoted to the investigation of 2,4,6-triaryl-1,2,5,6-tetrahydropyrimidine derivatives. A new facile approach to their synthesis based on the reaction of α,β-unsaturated ketones, carbonyl compounds and ammonia was developed. Some stereochemical features of the compounds obtained were fixed on the base of NMR data (including COSY and NOESY experiments). <p>

Title:Facile Synthesis of Aryl-Substituted 1,2,5,6-Tetrahydropyrimidines and Their Stereochemical Investigation
Creators:
Chebanov, Valentin A.
Muravyova, Elena A.
Sadchikova, Yulia V.
Desenko, Sergey M.
Chernenko, Vitaly N.
Kobzar, Kiril M.
Musatov, Vladimir I.
Uncontrolled Keywords:Heterocyclizations, Multicomponent reactions, Pyrimidines, Chalcones, Synthetic methods, Nitrogen heterocycles, Structure elucidation, 1,2,5,6-Tetrahydropyrimidines, NMR spectroscopy
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:69
Number:4
Page Range:pp. 897-904
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20040897UNSPECIFIED
ID Code:2250
Item Type:Article
Deposited On:06 Feb 2009 17:16
Last Modified:06 Feb 2009 16:17

Citation

Chebanov, Valentin A.; Muravyova, Elena A.; Sadchikova, Yulia V.; Desenko, Sergey M.; Chernenko, Vitaly N.; Kobzar, Kiril M.; Musatov, Vladimir I. (2004) Facile Synthesis of Aryl-Substituted 1,2,5,6-Tetrahydropyrimidines and Their Stereochemical Investigation. Collection of Czechoslovak Chemical Communications, 69 (4). pp. 897-904. ISSN 0010-0765

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