Low-Polarity Phytoecdysteroids from the Juice of Serratula coronata L. (Asteraceae)

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Title:Low-Polarity Phytoecdysteroids from the Juice of Serratula coronata L. (Asteraceae)
Creators:
Odinokov, Victor N.
Kumpun, Saowanee
Galyautdinov, Ilgiz V.
Evrard-Todeschi, Nathalie
Veskina, Natalya A.
Khalilov, Leonard M.
Girault, Jean-Pierre
Dinan, Laurence
Maria, Annick
Lafont, René
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 70, 12, pp. 2038-2052
Uncontrolled Keywords:<i>Serratula coronata</i> L. (<i>Asteraceae</i>), Phytochemistry, Ecdysone 22-acetate, Ecdysteroids, Steroids, Natural compounds isolation, NMR spectroscopy

Abstract

Eleven phytoecdysteroids have been isolated and identified from the low polarity fractions of <i>Serratula coronata</i> juice by a combination of column chromatography and HLPC. Four of them are new, i.e. ecdysone 22-acetate <strong>7</strong>, (25<i>S</i>)-inokosterone 26-acetate <strong>9</strong>, 20,22-<i>O</i>-(<i>R</i>-ethylidene)-20-hydroxyecdysone <strong>10</strong> and 20,22-<i>O</i>-(<i>R</i>-ethylidene)-ajugasterone C <strong>11</strong>. The biological activity of these new ecdysteroids in the <i>Drosophila melanogaster</i> B<sub>II</sub> cell bioassay is reported. <p>

Title:Low-Polarity Phytoecdysteroids from the Juice of Serratula coronata L. (Asteraceae)
Creators:
Odinokov, Victor N.
Kumpun, Saowanee
Galyautdinov, Ilgiz V.
Evrard-Todeschi, Nathalie
Veskina, Natalya A.
Khalilov, Leonard M.
Girault, Jean-Pierre
Dinan, Laurence
Maria, Annick
Lafont, René
Uncontrolled Keywords:<i>Serratula coronata</i> L. (<i>Asteraceae</i>), Phytochemistry, Ecdysone 22-acetate, Ecdysteroids, Steroids, Natural compounds isolation, NMR spectroscopy
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:70
Number:12
Page Range:pp. 2038-2052
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20052038UNSPECIFIED
ID Code:2454
Item Type:Article
Deposited On:06 Feb 2009 17:18
Last Modified:06 Feb 2009 16:18

Citation

Odinokov, Victor N.; Kumpun, Saowanee; Galyautdinov, Ilgiz V.; Evrard-Todeschi, Nathalie; Veskina, Natalya A.; Khalilov, Leonard M.; Girault, Jean-Pierre; Dinan, Laurence; Maria, Annick; Lafont, René (2005) Low-Polarity Phytoecdysteroids from the Juice of Serratula coronata L. (Asteraceae). Collection of Czechoslovak Chemical Communications, 70 (12). pp. 2038-2052. ISSN 0010-0765

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