Physicochemical Properties of 9-(Alkylsulfanyl)- and 9-(Arylsulfanyl)acridine Derivatives and Their Interaction with (2-Hydroxypropyl)cyclodextrins

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Title:Physicochemical Properties of 9-(Alkylsulfanyl)- and 9-(Arylsulfanyl)acridine Derivatives and Their Interaction with (2-Hydroxypropyl)cyclodextrins
Creators:
Němcová, Irena
Nesměrák, Karel
Kafková, Božena
Sejbal, Jan
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 71, 2, pp. 179-189
Uncontrolled Keywords:Sulfanylacridines, Inclusion complexes, Association constants, Aggregation, Cyclodextrins, Dissolution, Dissociation constants, NMR spectroscopy

Abstract

Acid-base properties and aggregations of 9-(alkylsulfanyl)- and 9-(arylsulfanyl)acridine derivatives were studied as a part of systematic study of physicochemical properties of these compounds synthesized as potential drugs. The effect of the (2-hydroxypropyl)cyclodextrins on these properties and their association with the acridines was also followed. <p>

Title:Physicochemical Properties of 9-(Alkylsulfanyl)- and 9-(Arylsulfanyl)acridine Derivatives and Their Interaction with (2-Hydroxypropyl)cyclodextrins
Creators:
Němcová, Irena
Nesměrák, Karel
Kafková, Božena
Sejbal, Jan
Uncontrolled Keywords:Sulfanylacridines, Inclusion complexes, Association constants, Aggregation, Cyclodextrins, Dissolution, Dissociation constants, NMR spectroscopy
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:71
Number:2
Page Range:pp. 179-189
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc20060179UNSPECIFIED
ID Code:2472
Item Type:Article
Deposited On:06 Feb 2009 17:19
Last Modified:06 Feb 2009 16:19

Citation

Němcová, Irena; Nesměrák, Karel; Kafková, Božena; Sejbal, Jan (2006) Physicochemical Properties of 9-(Alkylsulfanyl)- and 9-(Arylsulfanyl)acridine Derivatives and Their Interaction with (2-Hydroxypropyl)cyclodextrins. Collection of Czechoslovak Chemical Communications, 71 (2). pp. 179-189. ISSN 0010-0765

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