Chiral aliphatic hydroxy compounds in nature: A review of biological functions and practical applications

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Title:Chiral aliphatic hydroxy compounds in nature: A review of biological functions and practical applications
Creators:
Mozga, Tomáš
Prokop, Zbyněk
Chaloupková, Radka
Damborský, Jiří
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 74, 7-8, pp. 1195-1278
Uncontrolled Keywords:Drugs, Chemical communication, Chiral pool, Pheromones, Enantioselective enzymes, Hydroxy compounds, Odours, Natural products, Alcohols, Chiral compounds

Abstract

Chirality is a phenomenon that pervades the life on the Earth and has a tremendous importance for our daily lives. Many pharmaceuticals, agrochemicals, food additives, pheromones, fragrances and cosmetics are chiral. Chiral compounds play an essential role in biological systems, mainly for chemical communication among living organisms, serving as sex pheromones, aggregation pheromones, alarm pheromones, trail pheromones, attractants or repellent agents. This review summarizes our current knowledge of the biologically relevant chiral aliphatic hydroxy compounds, which are divided into eight classes according to their chemical structure: primary alcohols, secondary alcohols, tertiary alcohols, glycols and diols, hydroxy ketones, hydroxy carboxylic acids, hydroxy carboxylic esters and hydroxy amines. Information on biological functions and practical applications is summarized for each class. This information could be of interest to chemists, biochemists, biologists and pharmacists. A review with 475 references.

Title:Chiral aliphatic hydroxy compounds in nature: A review of biological functions and practical applications
Creators:
Mozga, Tomáš
Prokop, Zbyněk
Chaloupková, Radka
Damborský, Jiří
Uncontrolled Keywords:Drugs, Chemical communication, Chiral pool, Pheromones, Enantioselective enzymes, Hydroxy compounds, Odours, Natural products, Alcohols, Chiral compounds
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:74
Number:7-8
Page Range:pp. 1195-1278
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc2009038UNSPECIFIED
ID Code:4530
Item Type:Article
Deposited On:01 Sep 2009 12:41
Last Modified:01 Sep 2009 10:41

Citation

Mozga, Tomáš; Prokop, Zbyněk; Chaloupková, Radka; Damborský, Jiří (2009) Chiral aliphatic hydroxy compounds in nature: A review of biological functions and practical applications. Collection of Czechoslovak Chemical Communications, 74 (7-8). pp. 1195-1278. ISSN 0010-0765

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