Synthesis of polysubstituted 2,4-dimethylquinolines as potential antimalarial drugs

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Title:Synthesis of polysubstituted 2,4-dimethylquinolines as potential antimalarial drugs
Creators:
Parushev, Stoyan
Vlahov, Yoncho
Vlahov, Radoslav
Nickel, Peter
Snatzke, Günther
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 56, 5, pp. 1110-1115

Abstract

A synthetic way for obtaining 6-amino-2,4-dimethylquinoline derivatives from 2,5-dichloraniline by successive ring closure, nitration, aromatic substitution at so activated quinoline ring, followed by reduction of the nitro group to amino group and alkylation of the last is described.

Title:Synthesis of polysubstituted 2,4-dimethylquinolines as potential antimalarial drugs
Creators:
Parushev, Stoyan
Vlahov, Yoncho
Vlahov, Radoslav
Nickel, Peter
Snatzke, Günther
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:56
Number:5
Page Range:pp. 1110-1115
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19911110UNSPECIFIED
ID Code:5029
Item Type:Article
Deposited On:22 Feb 2010 11:28
Last Modified:22 Feb 2010 10:29

Citation

Parushev, Stoyan; Vlahov, Yoncho; Vlahov, Radoslav; Nickel, Peter; Snatzke, Günther (1991) Synthesis of polysubstituted 2,4-dimethylquinolines as potential antimalarial drugs. Collection of Czechoslovak Chemical Communications, 56 (5). pp. 1110-1115. ISSN 0010-0765

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