Structural analysis of biological macromolecular assemblies by electron microscopic techniques

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Title:Structural analysis of biological macromolecular assemblies by electron microscopic techniques
Creators:
Boublik, Miloslav
Mandiyan, Valsan
Tumminia, Santa J.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 56, 5, pp. 1130-1146

Abstract

The development of high resolution electron microscopic techniques and the introduction of quantitative image analysis has provided a direct basis for studying the structure of biological macromolecules. Apart from the determination of overall morphology, including 3-D image reconstruction, these techniques provide information on the internal architecture of biological macromolecular assemblies, the topography of functional sites, the interactions of their components and elemental microanalysis in situ. Thus, from a mere photographic recording system of the past, electron microscopy has evolved into a high resolution quantitative spectroscopic analytical method.

Title:Structural analysis of biological macromolecular assemblies by electron microscopic techniques
Creators:
Boublik, Miloslav
Mandiyan, Valsan
Tumminia, Santa J.
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:56
Number:5
Page Range:pp. 1130-1146
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19911130UNSPECIFIED
ID Code:5032
Item Type:Article
Deposited On:22 Feb 2010 11:28
Last Modified:22 Feb 2010 10:29

Citation

Boublik, Miloslav; Mandiyan, Valsan; Tumminia, Santa J. (1991) Structural analysis of biological macromolecular assemblies by electron microscopic techniques. Collection of Czechoslovak Chemical Communications, 56 (5). pp. 1130-1146. ISSN 0010-0765

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