Metal complexes of nitrogen-oxygen donor ligands as potential drugs

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Title:Metal complexes of nitrogen-oxygen donor ligands as potential drugs
Creators:
Ibrahim, Said A.
El-Gyar, Sahar A.
El-Gahami, Mohamed A.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 56, 6, pp. 1333-1339

Abstract

Twelve new complexes of Cu(II), Ni(II), Co(II) and Cd(II) with 5-phenyl, 5-<i>p</i>-tolyl and 5-aminothioacetimide-azo-8-hydroxyquinoline have been synthesized. The ligands act as bidentate (NO) chelating agents forming the bis-chelate complexes. Analytical, conductivity, spectral and thermal data are consistent with six coordinated structure in the case of Cu(II), Ni(II), Co(II) and four coordinate structure in the case of the analogues Cd(II). It is identified that the metal chelates possess enhanced antibacterial and antifungal activities relative to the free ligands.

Title:Metal complexes of nitrogen-oxygen donor ligands as potential drugs
Creators:
Ibrahim, Said A.
El-Gyar, Sahar A.
El-Gahami, Mohamed A.
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:56
Number:6
Page Range:pp. 1333-1339
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19911333UNSPECIFIED
ID Code:5055
Item Type:Article
Deposited On:22 Feb 2010 11:29
Last Modified:22 Feb 2010 10:29

Citation

Ibrahim, Said A.; El-Gyar, Sahar A.; El-Gahami, Mohamed A. (1991) Metal complexes of nitrogen-oxygen donor ligands as potential drugs. Collection of Czechoslovak Chemical Communications, 56 (6). pp. 1333-1339. ISSN 0010-0765

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