Antimycobacterial derivatives of tetrazole

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Title:Antimycobacterial derivatives of tetrazole
Creators:
Waisser, Karel
Vanžura, Jiří
Hrabálek, Alexandr
Vinšová, Jarmila
Grešák, Štefan
Hruška, Jiří
Odlerová, Želimíra
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 56, 11, pp. 2389-2394

Abstract

A synthesis of (1-phenyltetrazol-5-ylthio)acetic acid derivatives has been developed. Functional variations concern the carboxylic group and/or the 4 position of phenyl group. Most of the compounds prepared have been tested with regard to their antimycobacterial activity but the activities found are medium or low ones. However, (1-phenyltetrazol-5-ylthio)acetic acid is better than the antituberculotic isoniazid in the activity to <i>Mycobacterium avium</i>.

Title:Antimycobacterial derivatives of tetrazole
Creators:
Waisser, Karel
Vanžura, Jiří
Hrabálek, Alexandr
Vinšová, Jarmila
Grešák, Štefan
Hruška, Jiří
Odlerová, Želimíra
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:56
Number:11
Page Range:pp. 2389-2394
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19912389UNSPECIFIED
ID Code:5168
Item Type:Article
Deposited On:22 Feb 2010 11:32
Last Modified:22 Feb 2010 10:32

Citation

Waisser, Karel; Vanžura, Jiří; Hrabálek, Alexandr; Vinšová, Jarmila; Grešák, Štefan; Hruška, Jiří; Odlerová, Želimíra (1991) Antimycobacterial derivatives of tetrazole. Collection of Czechoslovak Chemical Communications, 56 (11). pp. 2389-2394. ISSN 0010-0765

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