Reaction of Ethyl 5-Substituted-2-furoylmalonates with Secondary Amines

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Title:Reaction of Ethyl 5-Substituted-2-furoylmalonates with Secondary Amines
Creators:
Kada, Rudolf
Bruncková, Jarmila
Bobál', Pavol
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 59, 6, pp. 1400-1407

Abstract

<p><i>In situ</i> prepared magnesium salts of ethyl malonate react with 5-X-2-furoyl chlorides (X = Br, NO<sub>2</sub>, C<sub>6</sub>H<sub>5</sub>S and C<sub>6</sub>H<sub>5</sub>SO<sub>2</sub>) to give the corresponding ethyl 5-X-2-furoylmalonates. On treatment of these compounds with secondary amines no nucleophilic substitution of the group X in position 5 of the furan nucleus took place but, instead, amides of 5-X-2-furancarboxylic acids were isolated.

Title:Reaction of Ethyl 5-Substituted-2-furoylmalonates with Secondary Amines
Creators:
Kada, Rudolf
Bruncková, Jarmila
Bobál', Pavol
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:59
Number:6
Page Range:pp. 1400-1407
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19941400UNSPECIFIED
ID Code:561
Item Type:Article
Deposited On:06 Feb 2009 17:01
Last Modified:06 Feb 2009 16:02

Citation

Kada, Rudolf; Bruncková, Jarmila; Bobál', Pavol (1994) Reaction of Ethyl 5-Substituted-2-furoylmalonates with Secondary Amines. Collection of Czechoslovak Chemical Communications, 59 (6). pp. 1400-1407. ISSN 0010-0765

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