Synthesis of Bicyclic Pyridine Tripeptides

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Title:Synthesis of Bicyclic Pyridine Tripeptides
Creators:
Attia, Abd El-Hamid
Abo-Ghalia, Mohamed H.
Abd El-Salam, Osama I.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 59, 6, pp. 1451-1457

Abstract

<p>Dinicotinic acid reacted with L-phenylalanine affording <i>N</i>-dinicotinoyl-bis-L-phenylalanine (<i>VII</i>). The same product was also obtained by mild alkaline hydrolysis of the corresponding ester <i>VI</i>. Coupling of <i>VII</i> with L-ornithine or L-ornithine methyl ester gave rise to the formation of the desired chiral bicyclic tripeptides <i>IIIa</i> and <i>IIIb</i> as enniatin analogues.

Title:Synthesis of Bicyclic Pyridine Tripeptides
Creators:
Attia, Abd El-Hamid
Abo-Ghalia, Mohamed H.
Abd El-Salam, Osama I.
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:59
Number:6
Page Range:pp. 1451-1457
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19941451UNSPECIFIED
ID Code:566
Item Type:Article
Deposited On:06 Feb 2009 17:01
Last Modified:06 Feb 2009 16:02

Citation

Attia, Abd El-Hamid; Abo-Ghalia, Mohamed H.; Abd El-Salam, Osama I. (1994) Synthesis of Bicyclic Pyridine Tripeptides. Collection of Czechoslovak Chemical Communications, 59 (6). pp. 1451-1457. ISSN 0010-0765

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