Structural and Adsorption Effects of Some Thiopurine and Thiopyrimidine Derivatives on their Catalytic Activity at the Mercury Electrode

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Title:Structural and Adsorption Effects of Some Thiopurine and Thiopyrimidine Derivatives on their Catalytic Activity at the Mercury Electrode
Creators:
Ibrahim, Mohamed Sayed
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 59, 7, pp. 1472-1482

Abstract

<p>6-Thiopurine, 6-thiopurine riboside, 6-thioguanine, 6-thioguanosine, 8-thioguanosine, 2-thiouracil, 4-thiouridine, 2-thiocytosine and 2-thiocytidine are investigated by means of DC polarography and coulometry. In acid medium they give a typical catalytic hydrogen discharge wave, as shown by its parameters and the regeneration of the depolarizer during the electrode process. At pH values above 4.2 a second catalytic wave appears. Both catalytic waves possess pronounced surface characteristics, most likely due to adsorption of the molecules with differing orientations on the electrode surface. The catalytic wave overlaps the reduction wave, which is placed in evidence under conditions where the catalytic effect is absent. Under the same conditions, 2-thiouracil was found to be catalytically inactive, but it induces catalytic hydrogen evolution in Co(II)-containing ammonia buffer. The present results indicate that the position of thio group yields also such distinct change in the catalytic activity of the investigated compounds.

Title:Structural and Adsorption Effects of Some Thiopurine and Thiopyrimidine Derivatives on their Catalytic Activity at the Mercury Electrode
Creators:
Ibrahim, Mohamed Sayed
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:59
Number:7
Page Range:pp. 1472-1482
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19941472UNSPECIFIED
ID Code:570
Item Type:Article
Deposited On:06 Feb 2009 17:02
Last Modified:06 Feb 2009 16:02

Citation

Ibrahim, Mohamed Sayed (1994) Structural and Adsorption Effects of Some Thiopurine and Thiopyrimidine Derivatives on their Catalytic Activity at the Mercury Electrode. Collection of Czechoslovak Chemical Communications, 59 (7). pp. 1472-1482. ISSN 0010-0765

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