Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by poly(4-vinylpyridinium tribromide)

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Title:Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by poly(4-vinylpyridinium tribromide)
Creators:
Ghorbani-Choghamarani, Arash
Zolfigol, Mohammad Ali
Hajjami, Maryam
Darvishi, Khorshid
Gholamnia, Laleh
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 75, 5, pp. 607-615
Uncontrolled Keywords:Hexamethyldisilazane (HMDS), Phenols, Protecting groups, Trimethylsilylation, Silylation, Alcohols, Protection, Poly(4-vinylpyridinium tribromide)

Abstract

A very efficient procedure for the protection of alcohols and phenols is presented. The mixture of 1,1,1,3,3,3-hexamethyldisilazane (HMDS) and catalytic amounts of poly(4-vinylpyridinium tribromide) was found to be effective for the trimethylsilylation of alcohols and phenols. Protection reaction is very simple and performs heterogeneously in acetonitrile at room temperature under mild conditions.

Title:Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by poly(4-vinylpyridinium tribromide)
Creators:
Ghorbani-Choghamarani, Arash
Zolfigol, Mohammad Ali
Hajjami, Maryam
Darvishi, Khorshid
Gholamnia, Laleh
Uncontrolled Keywords:Hexamethyldisilazane (HMDS), Phenols, Protecting groups, Trimethylsilylation, Silylation, Alcohols, Protection, Poly(4-vinylpyridinium tribromide)
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:75
Number:5
Page Range:pp. 607-615
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc2009560UNSPECIFIED
ID Code:5914
Item Type:Article
Deposited On:10 Jun 2010 11:48
Last Modified:10 Jun 2010 09:48

Citation

Ghorbani-Choghamarani, Arash; Zolfigol, Mohammad Ali; Hajjami, Maryam; Darvishi, Khorshid; Gholamnia, Laleh (2010) Protection of hydroxy groups as trimethylsilyl ethers using 1,1,1,3,3,3-hexamethyldisilazane (HMDS) catalyzed by poly(4-vinylpyridinium tribromide). Collection of Czechoslovak Chemical Communications, 75 (5). pp. 607-615.

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