Free Energies of Adsorption of Dipeptides and 2,5-Piperazinediones on Silica from Neutral Aqueous Solutions as Estimated from High-Performance Liquid-Chromatographic Retention Data

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Title:Free Energies of Adsorption of Dipeptides and 2,5-Piperazinediones on Silica from Neutral Aqueous Solutions as Estimated from High-Performance Liquid-Chromatographic Retention Data
Creators:
Basiuk, Vladimir A.
Gromovoy, Taras Yu.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 59, 8, pp. 1721-1728

Abstract

<p>The equilibrium constants (<i>K</i>) and free energies (-∆<i>G</i>) of adsorption of dipeptides and their cyclic derivatives, 2,5-piperazinediones, on silica from neutral aqueous solutions were calculated from their HPLC retention data on a silica gel column. For the majority of the dipeptides -∆<i>G</i> values were negative, ranging from -1&nbsp;170 to 430 J mol<sup>-1</sup>, and <i>K</i> &lt; 1, thus indicating a very weak adsorption. The 2,5-piperazinediones under study exhibited higher adsorbabilities (-∆<i>G</i> -1&nbsp;070 + 3&nbsp;030 J mol<sup>-1</sup>, <i>K</i> &gt; 1) as compared to the respective dipeptides. The effect of the α-substituent structure on the adsorbability is analyzed. A linear dependence of -∆<i>G</i> on the number of aliphatic carbon atoms in a sorbate molecule was observed for the series of dipeptides and 2,5-piperazinediones derived from bifunctional aliphatic amino acids.

Title:Free Energies of Adsorption of Dipeptides and 2,5-Piperazinediones on Silica from Neutral Aqueous Solutions as Estimated from High-Performance Liquid-Chromatographic Retention Data
Creators:
Basiuk, Vladimir A.
Gromovoy, Taras Yu.
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:59
Number:8
Page Range:pp. 1721-1728
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19941721UNSPECIFIED
ID Code:595
Item Type:Article
Deposited On:06 Feb 2009 17:02
Last Modified:06 Feb 2009 16:02

Citation

Basiuk, Vladimir A.; Gromovoy, Taras Yu. (1994) Free Energies of Adsorption of Dipeptides and 2,5-Piperazinediones on Silica from Neutral Aqueous Solutions as Estimated from High-Performance Liquid-Chromatographic Retention Data. Collection of Czechoslovak Chemical Communications, 59 (8). pp. 1721-1728. ISSN 0010-0765

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