A chronoamperometric study of the oxidative nucleation of niazid and isoniazid on mercury electrodes in basic solutions

[img]PDF - Authorized users only
Language: English
651Kb
Title:A chronoamperometric study of the oxidative nucleation of niazid and isoniazid on mercury electrodes in basic solutions
Creators:
Ruiz Montoya, Mercedes
Pintado, Sara
Rodríguez Mellado, José Miguel
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 76, 6, pp. 755-762
Uncontrolled Keywords:Adsorption, Pyridine hydrazides, Nucleation, Oxidation, Isoniazid, Electrochemistry, Electrode kinetics, Niazid

Abstract

Using chronoamperometric measurements at pH 12 it is shown that the oxidation mechanism of niazid adsorbed on the mercury electrode changes with respect to the mechanism reported in the literature for the electrooxidation of the molecules reaching the electrode by diffusion. A compact monolayer of niazid molecules is formed on the electrode surface, being the hydrazide oxidized through a two-electron process. The oxidation product is not able to dissociate a H<sup>+</sup> ion, and the oxidation process does not proceeds beyond. For isoniazid the monolayer never becomes compact.

Title:A chronoamperometric study of the oxidative nucleation of niazid and isoniazid on mercury electrodes in basic solutions
Creators:
Ruiz Montoya, Mercedes
Pintado, Sara
Rodríguez Mellado, José Miguel
Uncontrolled Keywords:Adsorption, Pyridine hydrazides, Nucleation, Oxidation, Isoniazid, Electrochemistry, Electrode kinetics, Niazid
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:76
Number:6
Page Range:pp. 755-762
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc2011056UNSPECIFIED
ID Code:6612
Item Type:Article
Deposited On:08 Jun 2011 11:39
Last Modified:08 Jun 2011 09:40

Citation

Ruiz Montoya, Mercedes; Pintado, Sara; Rodríguez Mellado, José Miguel (2011) A chronoamperometric study of the oxidative nucleation of niazid and isoniazid on mercury electrodes in basic solutions. Collection of Czechoslovak Chemical Communications, 76 (6). pp. 755-762.

Repository Staff Only: item control page