Synthesis of Some m-Substituted 1-Phenyl-6-azauracils

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Title:Synthesis of Some m-Substituted 1-Phenyl-6-azauracils
Creators:
Slouka, Jan
Bekárek, Vojtěch
Hlaváč, Jan
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 59, 12, pp. 2741-2746

Abstract

<p>Many 1-aryl-6-azauracils derivatives were prepared so far, among them the representation of <i>m</i>-substituted 1-phenyl derivatives is relatively poor. In this communication we report on the synthesis of the starting material - dicarbamate <i>I</i>, which was used for the preparation of some new 1-phenyl-6-azauracil derivatives <i>II</i>, containing simple nitrogeneous group in <i>m</i>-position. We focused also on the compounds <i>III</i> having two 6-azauracil rings mutually bonded in <i>m</i>-position to the benzene ring. These compounds can form hydrogen bonds simultaneously with two bonding centres of fitted substrate and so they can serve as model compounds for the interaction studies. From this type of compounds the dinitrile <i>IIIa</i> is known so far.

Title:Synthesis of Some m-Substituted 1-Phenyl-6-azauracils
Creators:
Slouka, Jan
Bekárek, Vojtěch
Hlaváč, Jan
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:59
Number:12
Page Range:pp. 2741-2746
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19942741UNSPECIFIED
ID Code:693
Item Type:Article
Deposited On:06 Feb 2009 17:03
Last Modified:06 Feb 2009 16:03

Citation

Slouka, Jan; Bekárek, Vojtěch; Hlaváč, Jan (1994) Synthesis of Some m-Substituted 1-Phenyl-6-azauracils. Collection of Czechoslovak Chemical Communications, 59 (12). pp. 2741-2746. ISSN 0010-0765

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