Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes

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Title:Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes
Creators:
Vyskočil, Vlastimil
Jiránek, Ivan
Daňhel, Aleš
Zima, Jiří
Barek, Jiří
Wang, Joseph
Pecková, Karolina
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 76, 12, pp. 1991-2004
Uncontrolled Keywords:Solid phase extraction, 8-Nitroquinoline, Analytical methods, 6-Nitroquinoline, 5-Nitroquinoline, Mercury electrodes, Polarography, Voltammetry, Electrochemistry, Spiked water samples

Abstract

Electrochemical behavior of genotoxic nitro derivatives of quinoline, namely 5-nitroquinoline (5-NQ), 6-nitroquinoline (6-NQ) and 8-nitroquinoline (8-NQ), was investigated by DC tast polarography (DCTP) and differential pulse polarography (DPP), both at a classical dropping mercury electrode (DME), and by differential pulse voltammetry (DPV) and adsorptive stripping differential pulse voltammetry (AdSDPV), both at a miniaturized hanging mercury drop minielectrode (HMDmE), in buffered aqueous (for 5-NQ) or aqueous-methanolic (for 6-NQ and 8-NQ) solutions. Optimum conditions were found for the determination of 5-NQ, 6-NQ and 8-NQ by DCTP at DME (with limits of quantification, <i>L</i><sub>Q</sub> ≈ 9 × 10<sup>–7</sup>, 3 × 10<sup>–7</sup> and 2 × 10<sup>–6</sup> mol l<sup>–1</sup>, respectively), by DPP at DME (<i>L</i>Q ≈ 1 × 10<sup>–8</sup>, 9 × 10<sup>–8</sup> and 1 × 10<sup>–7</sup> mol l<sup>–1</sup>, respectively), by DPV at HMDmE (<i>L</i>Q ≈ 2 × 10<sup>–8</sup>, 1 × 10<sup>–7</sup> and 1 × 10<sup>–7</sup> mol l<sup>–1</sup>, respectively), and by AdSDPV at HMDmE (<i>L</i>Q ≈ 1 × 10<sup>–8</sup> mol l<sup>–1</sup> for 8-NQ; an attempt at increasing the sensitivity using AdSDPV at HMDmE was not successful for 5-NQ and 6-NQ). Practical applicability of the developed methods was verified on the direct determination of the studied compounds in model samples of drinking and river water in submicromolar concentrations and on the determination in model samples of drinking and river water using preliminary separation and preconcentration by solid phase extraction (SPE) in nanomolar concentrations.

Title:Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes
Creators:
Vyskočil, Vlastimil
Jiránek, Ivan
Daňhel, Aleš
Zima, Jiří
Barek, Jiří
Wang, Joseph
Pecková, Karolina
Uncontrolled Keywords:Solid phase extraction, 8-Nitroquinoline, Analytical methods, 6-Nitroquinoline, 5-Nitroquinoline, Mercury electrodes, Polarography, Voltammetry, Electrochemistry, Spiked water samples
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:76
Number:12
Page Range:pp. 1991-2004
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc2011173UNSPECIFIED
ID Code:7270
Item Type:Article
Deposited On:31 Jul 2012 18:22
Last Modified:31 Jul 2012 16:23

Citation

Vyskočil, Vlastimil; Jiránek, Ivan; Daňhel, Aleš; Zima, Jiří; Barek, Jiří; Wang, Joseph; Pecková, Karolina (2011) Polarographic and voltammetric determination of genotoxic nitro derivatives of quinoline using mercury electrodes. Collection of Czechoslovak Chemical Communications, 76 (12). pp. 1991-2004.

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