Synthesis of trans β-Lactams of Estrane Series

[img]PDF - Authorized users only
Language: English
87Kb
Title:Synthesis of trans β-Lactams of Estrane Series
Creators:
Siddiqui, Abdul U.
Satyanarayana, Yelluru
Siddiqui, Abdul H.
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 60, 7, pp. 1186-1190

Abstract

<p>17,17-Ethylenedioxy-1,3,5(10)-estratrien-3β-ol (<i>I</i>) was converted into ethyl ester <i>II</i> by reaction with ethyl chloroacetate in the presence of potassium. The ethyl ester <i>II</i> on reaction with hydrazine gave hydrazide <i>III</i>, which on condensation with aromatic aldehydes gave Schiff bases <i>IVa</i>-<i>IVd</i>. The reaction of Schiff bases <i>IVa</i>-<i>IVd</i> with chloroacetyl chloride in the presence of triethylamine afforded β-lactams <i>Va</i>-<i>Vd</i>.

Title:Synthesis of trans β-Lactams of Estrane Series
Creators:
Siddiqui, Abdul U.
Satyanarayana, Yelluru
Siddiqui, Abdul H.
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:60
Number:7
Page Range:pp. 1186-1190
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19951186UNSPECIFIED
ID Code:815
Item Type:Article
Deposited On:06 Feb 2009 17:04
Last Modified:06 Feb 2009 16:04

Citation

Siddiqui, Abdul U.; Satyanarayana, Yelluru; Siddiqui, Abdul H. (1995) Synthesis of trans β-Lactams of Estrane Series. Collection of Czechoslovak Chemical Communications, 60 (7). pp. 1186-1190. ISSN 0010-0765

Repository Staff Only: item control page