Neutralization Dialysis. Problems and Outlook

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Title:Neutralization Dialysis. Problems and Outlook
Creators:
Tishchenko, Galina A.
Denisov, Genadii A.
Shataeva, Larisa K.
Bleha, Miroslav
Journal or Publication Title:
Collection of Czechoslovak Chemical Communications, 60, 11, pp. 1888-1904

Abstract

<p>Neutralization dialysis (ND) of model systems containing 0.1-0.5 M NaCl and various high-molecular-weight synthetic or natural substances have been investigated. Desalination experiments were carried out in a three-compartment spiral module equipped with heterogeneous Ralex or homogeneous Neosepta membranes. Practically complete desalination proceeds due to the neutralization reaction in the desalination compartment. The time of desalination depends only on the membrane permeability and on the initial salt concentration in solution. An important feature hindering larger application of this method is sharp pH changes occurring in the desalination solution. This phenomenon predicted theoretically is mainly caused by the difference in diffusivities of H<sup>+</sup>/Na<sup>+</sup> and OH<sup>-</sup>/Cl<sup>-</sup> ion pairs. Independently of the type of membrane and desalinated solution, pH value jumps into acidic region at the beginning of the ND. In the course of the process the pH value increases and the ND proceeds mostly at pH &lt; 7. On the basis of theoretical prediction, an experimental method consisting in adjustment of acid concentration is proposed, which makes it possible to maintain constant pH in the desalination compartment. The convenience of this method was demonstrated by the ND of protein solutions.

Title:Neutralization Dialysis. Problems and Outlook
Creators:
Tishchenko, Galina A.
Denisov, Genadii A.
Shataeva, Larisa K.
Bleha, Miroslav
Divisions:Life and Chemical Sciences > Institute of Organic Chemistry and Biochemistry > Collection of Czechoslovak Chemical Communications
Journal or Publication Title:Collection of Czechoslovak Chemical Communications
Volume:60
Number:11
Page Range:pp. 1888-1904
ISSN:0010-0765
E-ISSN:1212-6950
Publisher:Institute of Organic Chemistry and Biochemistry
Related URLs:
URLURL Type
http://dx.doi.org/10.1135/cccc19951888UNSPECIFIED
ID Code:878
Item Type:Article
Deposited On:06 Feb 2009 17:04
Last Modified:06 Feb 2009 16:04

Citation

Tishchenko, Galina A.; Denisov, Genadii A.; Shataeva, Larisa K.; Bleha, Miroslav (1995) Neutralization Dialysis. Problems and Outlook. Collection of Czechoslovak Chemical Communications, 60 (11). pp. 1888-1904. ISSN 0010-0765

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